SARS-CoV-2 Spike Glycoprotein-S1 RBD (319-541, biotinylated) recombinant Protein
Please log in to see the special conditions of your institution.
Phone: +49 (0) 40 . 43 20 84 48 0
Novel Coronavirus 2019 Glycoprotein-S1 Receptor Binding Domain (Amino Acid 319-541) biotinylated, recombinant
Description of SARS-CoV-2 Spike Glycoprotein-S1 RBD (319-541, biotinylated)
Recombinant Spike Glycoprotein S1 Receptor Binding Domain, derived from HEK293 cells is a glycosylated protein consisting of Amino acid 319-341, fused to A His-Tag and Avi-Tag at the C-terminal. It is derived from the Wuhan-Hu-1 strain. SARS-CoV-2, formerly termed 2019-nCOV, causes the pandemic COVID-19 disease, a viral pneumonia. The production in HEK293 cells ensures the most authentic post translational modifications.
The SARS-CoV-2 shares an 87% identity to two bat-derived severe acute respiratory syndrome 2018 (SARS-like) coronaviruses found in Zhoushan of eastern China. It is more distant from SARS-CoV (79%) identity and MERS-CoV (50%) identity. SARS-CoV-2 has an analogous receptor-binding domain-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.
While bats are possibly the host of SARS-CoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the SARS-CoV-2 is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
We recommend a quick spin followed by reconstitution in water to a concentration of at least 100µg/ml, this solution can then be further diluted. Do not vortex.
The protein is stable until the lot specific expiry date if stored at -24°C or below. At room temperature it is stable for at least two weeks and to avoid repeated freeze thaw cycles we recommend short term (1-2 weeks) storage at 2°C - 4°C. Please avoid repeated freeze thaw cycles.
To buy SARS-CoV-2 Spike Glycoprotein-S1 RBD (319-541, biotinylated) please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button »Shopping List & Order Form« to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.
All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.
Errors, changes and availability excepted.
Paying by bank transfer
We ship with UPS
Free shipping for orders above 500 € within Germany