Human/Murine/Rat Irisin recombinant Protein

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Synonyms

Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Irisin, FRCP2, FNDC5.

Description of Human/Murine/Rat Irisin

Fibronectin Type III Domain Containing 5 Human Recombinant produced in yeast is a glycosylated, polypeptide chain containing 110 amino acids and having a molecular mass of 20-25 kDa.

Biological Activity

The biological activity of recombinant human irisin was measured by the ability to induce UCP-1 expression of adipocytes. The specific activity is 10ng/ml.

Reconstitution

It is recommended to reconstitute the lyophilized Fibronectin Type III Domain Containing 5 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Fibronectin Type III Domain Containing 5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FNDC5 should be stored at 4°C between 2-7 days and for future use below -18°C. Please avoid repeated freeze-thaw cycles.

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Amino Acid Sequence

S_P__S__A_ _P__V__N__ V__T__V__R __H__L__K_ _A__N__S__ A__V__V__S _ W__D__V_ _L__E__D__ E__V__V__I __G__F__A_ _I__S__Q__ Q__K__K__D _V__R__M__ L__R__F__I __Q__E__V_ _N__T__T__ T__R__S__C __A__L__W_ _D__L__E_ _E__D__T__ E__Y__I__V __H__V__Q_ _A__I__S__ I__Q__G__Q _ S__P__A_ _S__E__P__ V__L__F__K __T__P__R_ _E__A__E__ K__M__A__S _K__N__K__ D__E__V__T __M__K__E

Shipped at room temperature

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