Human Relaxin-2, His-Tag, liquid recombinant Protein

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Synonyms

Prorelaxin H2, RLN2, H2, RLXH2, H2-RLX.

Description of Human Relaxin-2, His-Tag, liquid

Recombinant human Relaxin-2, His-Tag liquid is a nonglycosylated 20.7 kDa disulfide linked heterodimeric protein consisting of 161 amino acids fused to a 23aa His-Tag at the N-terminus. It consists of amino acids 25 to 185 therefore Relaxin B-chain (29aa), natural connecting Peptide (101aa), Relaxin A-chain (24aa). Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth.

Biological Activity

Data not available.

Stability

The undiluted product can be stored at 4°C for up to 4 weeks and at -20°C until the expiry date. For long term storage we recommend to add 0,1% HSA (order number: 2835.955.xyz or 2835.958.xyz) and store in suitable working aliquots at -20°C to -80°C. Please avoid repeated freeze-thaw cycles.

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Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFC

Shipped with ice packs

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