Anti-Human KDR / VEGFR-2 (#4) (MAB) Monoclonal Antibody

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Product Overview, Sizes and Prices

 

Monoclonal Antibodies (MAB)

Synonyms: vascular endothelial growth factor receptor-2 , KDR, FLK1, CD309, VEGF receptor 2, VEGFR2, kinase insert domain protein receptor

Source: Mouse

Physical state: Lyophilized

Clone: AB-531J7

Isotype: IgG1

Manufacturer:  Active Bioscience

Article No. Size Price  
1621.650.100 100 µg 230 €

 

 

Product Details

Synonyms

vascular endothelial growth factor receptor-2 , KDR, FLK1, CD309, VEGF receptor 2, VEGFR2, kinase insert domain protein receptor

 

Description of Anti-Human KDR / VEGFR-2 (#4) (MAB)

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

 

Biological Activity

ELISA: Use at 1-10 µg/ml. Western blotting: Use at 2-5 µg/ml. Immunohistochemistry: Use at 6-30 µg/ml. Immunofluorescence: Use at 1-2 µg/ml. FACS analysis: Use at 2-5 µg/ml.

 

Reconstitution

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 1.0 mg/ml.

 

Shipping symbol Shipped at room temperature

 

 

 

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

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Errors, changes and availability excepted.

 

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

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