EN
Anti-Human TIE-2, bt (#tek2) (MAB) Monoclonal Antibody
Product Overview, Sizes and Prices | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Monoclonale Antibody (MAB) Synonyms: TEK, TIE2, VMCM, TIE-2, VMCM1, CD202B Source: Mouse Clone: AB-ufl3 Isotype: IgG1 Manufacturer: |
|
|||||||||
Active Bioscience
Produktdetails
Synonyms
TEK, TIE2, VMCM, TIE-2, VMCM1, CD202B
Description of Anti-Human TIE-2, bt (#tek2) (MAB)
Tie-1/Tie and Tie-2/Tek are receptor tyrosine kinases with unique structural characteristics including two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains, followed by three fibronectin type III-like repeats in the extracellular region, and a split tyrosine kinase domain in the cytoplasmic region. Tie-2 is involved in vascular stabilization and remodeling. Although less well understood, Tie-1 may also act as an ANG receptor, possibly in complex with Tie-2. Human Tie-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Tie-2 is a receptor for the angiopoietin (ANG) family: ANG-1, ANG-2, and ANG-3 (mouse)/-4 (human). Ang-2 has been reported to act as an antagonist for Ang-1. Mice engineered to overexpress Ang-2 or to lack Ang-1 or Tie-2 display similar angiogenesis defects.
Biological Activity
FACS analysis and cell sorting: Use at 2-5 µg/ml.
Reconstitution
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Shipped at room temperature
Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.
To buy Anti-Human TIE-2, bt (#tek2) (MAB) Monoclonal Antibody please click on the Shopping List Symbol right from the indicated price. This will add Anti-Human TIE-2, bt (#tek2) (MAB) Monoclonal Antibody to your Shopping List. You can then click on the button »Shopping List & Order Form« to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.
For business customers only. All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.
Errors, changes and availability excepted.
Payment Methods
Paying by bank transfer
