Anti-Human CCBE1 Polyclonal Antibody

Please log in to see the special conditions of your institution.

 

Mitarbeiterfoto

+49 (0) 40 . 43 20 84 48 0

 

Product Overview, Sizes and Prices

 

Polyclonal Antibody (PAB)

Synonyms: collagen and calcium binding EGF domains 1, KIAA1983

Source: Rabbit

Clone: AB-Sbccju!JH

Manufacturer:  Active Bioscience

Article No. Size Price  
4383.852.100 100 µg 175 €
4383.852.200 200 µg 285 €

 

 

Product Details

Synonyms

collagen and calcium binding EGF domains 1, KIAA1983

 

Description of Anti-Human CCBE1

The lymphatic system comprises a vascular system separate from the cardiovascular system, essential for immune responses, fluid homeostasis and fat absorption. Lymphatic vessels develop in a complex process termed lymphangiogenesis that involves budding, migration and proliferation of lymphatic endothelial progenitor cells. A few genes, such as FLT4, FOXC2 and SOX18, are known to be critically involved in lymph vessel formation in humans. Lymphedema, lymphangiectasias, mental retardation and unusual facial characteristics define the autosomal recessive Hennekam syndrome. Homozygosity mapping identified a critical chromosomal region containing ccbe1, encoding Collagen and Calcium-Binding EGF-domain-1, a secreted protein which is required for embryonic lymphangiogenesis in zebrafish. ccbe1 is not expressed in endothelial cells of lymph vessels, and it may be a component of the extracellular matrix. In zebrafish, ccbe1 expression was observed along the earliest migration routes of endothelial cells that sprout from the posterior cardinal vein and migrate circuitously before developing into lymphatic vessels. ccbe1 might therefore be involved in guidance of these migrating cells.

 

Biological Activity

Western Blot: Use 2-5 µg/ml

 

Reconstitution

Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

 

Shipping symbol Shipped at room temperature

 

 

 

 

 

 

 

To buy Anti-Human CCBE1 please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button »Shopping List & Order Form« or the Shopping List Symbol in the top navigation to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.

 

All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.

 

Errors, changes and availability excepted.

 

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

This website uses cookies to store your Personal Shopping List. By using our website you accept the use of session cookies. Learn more
I accept all necessary cookies