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Anti-Murine PlGF Polyclonal Antibody
Product Overview, Sizes and Prices |
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Polyclonal Antibody (PAB) Synonyms: Pgf, PlGF, Plgf, AI854365, placental growth factor Source: Rabbit Clone: AB-Sbccju!JH Manufacturer: |
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Active Bioscience
Product Details
Synonyms
Pgf, PlGF, Plgf, AI854365, placental growth factor
Description of Anti-Murine PlGF
Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65% amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.
Biological Activity
Use 1:200
Reconstitution
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Shipped at room temperature
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Payment Methods
Paying by bank transfer
