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BMP7 Selective Inhibitor
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Selective Inhibitor Source: Chemical Synthesis Purity: ≥ 95% (HPLC) Physical State: Lyophilized Manufacturer: |
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PeptiGrowth
Produktdetails
Description of BMP7 Selective Inhibitor
Enabled BMP7 signaling to be inhibited selectively, which was not possible with Noggin! May be useful for detailed analysis and regulation of BMP signaling, as well as for development of novel cell differentiation processes!
Physcial State
Lyophilized from 0.2 µm filtered DMSO solution.
Biological Activity
Measured by its ability to inhibit smad1 phosphorylation induced by BMP4 (2.6 ng/mL) or BMP7 (157.5 ng/mL) in A549 cell. Expected IC50 for BMP7 is ~30 ng/mL under this condition. Determine optimal concentrations for individual applications.
Reconstitution
Reconstitute at 100~200 µg/mL in DMSO. Centrifuge the vial before opening. Rinse the inside of the vial thoroughly with DMSO. Example: a 100 µg/mL solution can be prepared by reconstituting 5 µg of peptide in 50 µL DMSO.
Shipped with ice packs
| Fig. 1: BMP4 (2.6 ng/mL) stimulation |
| Fig. 2: BMP7 (157.5 ng/mL) stimulation |
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Errors, changes and availability excepted.
Payment Methods
Paying by bank transfer
