Cynomolgus Monkey Haptoglobin

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	Proteins Synonyms: Zonulin, HPT, HP, BP, HP2ALPHA2, HPA1S Source: Cynomolgus Monkey Plasma Purity: ≥ 95% by SDS-PAGE Physical State: Salt-free lyophilized solid. Manufacturer:  Athens Research & Technology	Article No. Size Price   16-16-080116-CM-1MG 1 mg 705 € Please inquire for other vial sizes and custom vialing.

 

 

Produktdetails

Synonyms

Zonulin, HPT, HP, BP, HP2ALPHA2, HPA1S

 

Description of Cynomolgus Monkey Haptoglobin

Cynomolgus monkey haptoglobin is a plasma glycoprotein with a molecular weight around 86 kDa, structurally composed of α and β subunits linked by disulfide bonds. Its primary function is to bind free hemoglobin released during red blood cell turnover, forming a stable Hp-Hb complex that prevents hemoglobin-induced oxidative tissue damage and facilitates safe clearance by the reticuloendothelial system. This antioxidant role is crucial in protecting tissues from oxidative stress and inflammation. Haptoglobin exhibits genetic polymorphism, resulting in different phenotypes that can influence its structural and functional properties. Altered haptoglobin function or levels are associated with diseases such as hemolytic anemia, cardiovascular disease, and inflammatory disorders, as inefficient hemoglobin clearance can exacerbate oxidative injury and inflammation. In biomedical research, cynomolgus monkey haptoglobin is used as a critical reagent in immunoassays, complement-dependent cytotoxicity assays, and as a reference protein for studying cross-species immune responses, due to its close similarity to human haptoglobin.

 

Source

Monkey plasma was obtained from healthy animals of US origin and under the care of a registered veterinarian. Prepared from donor monkeys that have been individually tested for B-Virus (Herpes Virus Simiae) and found to be negative

 

Storage

For long term, store Cynomolgus Monkey Haptoglobin at ≤ -20°C.

 

Applications

ELISA, Protein Chemistry, Inflammation, Sickle Cell Anemia, Glycosylation, Stroke, Central Nervous System Injury, Diabetes, Cardiovascular Disease, In Vitro Diagnostic, Iron Metabolism, Cancer.

 

Shipped with ice packs

 

 

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Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

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