Human FGF-10 / KGF-2 recombinant Protein

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Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: KGF-2, FGFA

Source: E. coli

Biological activity: ≥ 2 x 106 units/mg

Purity: ≥ 95 % (SDS-PAGE, silver stained)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1379.950.010 10 g 90 €
1379.950.025 25 g 150 €
1379.950.050 50 g 260 €
1379.950.100 100 g 450 €
1379.950.250 250 g 790 €
1379.950.500 500 g 1.350 €
1379.950.199 1 mg 2.250 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

KGF-2, FGFA

 

Description of Human FGF-10 / KGF-2

Recombinant Human Fibroblast Growth Factor-10 (FGF-10 or KGF-2) is a 170 amino acid protein, with a molecular mass of 19,3 kDa. It is a heparin-binding growth factor belonging to the fibroblast growth factor (FGF) family most related to KGF/FGF-7. FGF family members possess extensive mitogenic and cell survival functions, and are involved in various biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 is expressed during development and preferentially in adult lungs. It signals through FGFR 2b.

 

Biological Activity

Assay 1: The ED50 of ≤ 0.5ng/ml was determined by the dose-dependent stimulation of thymidine uptake of BaF3 cells expressing FGFRs. It corresponds to a specific activity of ≥ 2.0 x 106 units/mg.
Assay 2: An ED50 of 0,5-1,0 ng/ml was determined by the FGF-10 induced proliferation of 4MBr-5 cells.

 

Reconstitution

We recommend a quick spin followed by reconstitution in water to a concentration of at least 50 g/ml. Do not vortex. This solution can be stored at 2-8C for up to 1 week or in working aliquots at -20C to -80C. Working aliquots should be at the highest practical concentration. For long term storage we recommend to add at least 0.1% HSA (order number: 2835.955.xyz or 2835.958.xyz) or BSA.

 

Stability

The lyophilized protein is stable at room temperature for up to 1 month and at least until the lot specific expiry date if kept below -18C. Reconstituted FGF-10 should be stored in working aliquots at -20C to -80C if possible with carrier protein. Please avoid repeated freeze-thaw cycles.

 

Amino Acid Sequence

MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

 

To buy Human FGF-10 / KGF-2 (W1379950010, W1379950025, W1379950050, W1379950100, W1379950250, W1379950500, W1379950199) please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button Shopping List & Order Form to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.

 

All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.

 

Errors, changes and availability excepted.

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500  within Germany

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