Human FGF-22 recombinant Protein

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Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: Fibroblast growth factor 22

Source: E. coli

Biological activity: see below

Purity: ≥ 97 % (SDS-PAGE, RP-HPLC)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1386.950.002 2 g 60 €
1386.950.010 10 g 159 €
1386.950.199 1 mg 4.590 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

Fibroblast growth factor 22

 

Description of Human FGF-22

Recombinant Human Fibroblast Growth Factor-22 (FGF-22) is a 149 amino acid protein, with a molecular mass of 17,3 kDa. It is a secreted a heparin-binding growth factor belonging to the fibroblast growth factor (FGF) family. FGF family members possess extensive mitogenic and cell survival functions, and are involved in various biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.

 

Biological Activity

An ED50 of 50-250 ng/ml was determined by the FGF-22 induced proliferation of 4MBr-5 rhesus monkey epithelial cells.

 

Reconstitution

We recommend a quick spin followed by reconstitution in water to a concentration of at least 100 g/ml. Do not vortex. This solution can be stored at 2-8C for up to 1 week or in working aliquots at -20C to -80C. Working aliquots should be at the highest practical concentration. For long term storage we recommend to add at least 0.1% HSA (order number: 2835.955.xyz or 2835.958.xyz) or BSA.

 

Stability

The lyophilized protein is stable at room temperature for up to 1 month and at least until the lot specific expiry date if kept below -18C. Reconstituted FGF-9 should be stored in working aliquots at -20C to -80C if possible with carrier protein. Please avoid repeated freeze thaw cycles.

 

Amino Acid Sequence

MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTV DCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

 

To buy Human FGF-22 please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button Shopping List & Order Form to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.

 

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Errors, changes and availability excepted.

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500  within Germany

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