Human FGF-6 recombinant Protein

Please log in to see the special conditions of your institution.

 

Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: Fibroblast Growth Factor 6, Heparin Secretory-Transforming Protein 2, Heparin-Binding Growth Factor 6, HBGF-6, HSTF-2

Source: E. coli

Biological activity: ≥ 2 x 106 units/mg

Purity: ≥ 98 % (SDS-PAGE, HPLC)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1374.950.005 5 g 60 €
1374.950.025 25 g 159 €
1374.950.199 1 mg 2.390 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

Fibroblast Growth Factor 6, Heparin Secretory-Transforming Protein 2, Heparin-Binding Growth Factor 6, HBGF-6, HSTF-2

 

Description of Human FGF-6

Recombinant Human FGF-6 is a 169 amino acid protein, with a molecular mass of 18,9 kDa. Fibroblast Growth Factor-6 (FGF-6) is a secreted, heparin-binding growth factor belonging to the fibroblast growth factor (FGF) family. FGF family members possess extensive mitogenic and cell survival functions, and are involved in various biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4. The FGF6 gene displays oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of the FGF6 gene displays a restricted expression profile predominantly in the myogenic lineage, suggesting a role in muscle regeneration or differentiation.

 

Biological Activity

The ED50 of ≤ 0.5ng/ml was determined by the dose-dependent stimulation of thymidine uptake of BaF3 cells. It corresponds to a specific activity of ≥ 2.0 x 106 units/mg.

 

Reconstitution

We recommend a quick spin followed by reconstitution in water to a concentration of at least 100 g/ml. Do not vortex. This solution can be stored at 2-8C for up to 1 week or in working aliquots at -20C to -80C. Working aliquots should be at the highest practical concentration. For long term storage we recommend to add at least 0.1% HSA (order number: 2835.955.xyz or 2835.958.xyz) or BSA.

 

Stability

The lyophilized protein is stable at room temperature for up to 1 month and at least until the lot specific expiry date if kept below -18C. Reconstituted FGF-6 should be stored in working aliquots at -20C to -80C if possible with carrier protein. Please avoid repeated freeze thaw cycles.

 

Amino Acid Sequence

MGTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

 

To buy Human FGF-6 please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button Shopping List & Order Form to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.

 

All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.

 

Errors, changes and availability excepted.

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500  within Germany

This website uses cookies to store your Personal Shopping List. By using our website you accept the use of session cookies. Learn more
Got it