Human G-CSF recombinant Protein
CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim.
Description of Human G-CSF
Recombinant human G-CSF is an 18.8 kDa protein consisting of 175 amino acid residues. G-CSF is a hematopoietic factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate haematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive.
The ED50 of ≤ 0.1ng/ml was determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells. It corresponds to a specific activity of ≥ 1.0 x 108 IU/mg.
We recommend a quick spin followed by reconstitution in sterile 20mM Acetic acid (AcOH) r to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous solutions and stored at 4°C for 1 week or below -20°C for future use.
The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted G-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Please avoid repeated freeze-thaw cycles.
Amino Acid Sequence
MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
Shipped at room temperature
To buy Human G-CSF (W1430950002, W1430950010, W1430950100, W1430950199) please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button »Shopping List & Order Form« or the Shopping List Symbol in the top navigation to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable. Human G-CSF is an alternative for the no longer available Promokine G-CSF, human, recombinant (C-60435).
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