Human Heregulin beta-1 / Neuregulin-1 recombinant Protein

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Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: Neuregulin-1, Heregulin-b1, NRG1-B1, NRG1 B1.

Source: E. coli

Biological activity: ≥ 2 x 106 units/mg

Purity: ≥ 97 % (SDS-PAGE, RP-HPLC)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1467.950.010 10 µg 60 €
1467.950.050 50 µg 159 €
1467.950.199 1 mg 1.195 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

Neuregulin-1, Heregulin-b1, NRG1-B1, NRG1 B1.

 

Description of Human Heregulin beta-1 / Neuregulin-1

Recombinant Human Neuregulin-1/Heregulin-b1 produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 177-241) containing 65 amino acids and having a total molecular mass of 7.5kDa. NRG1-B1 is purified by proprietary chromatographic techniques.

 

Biological Activity

The ED50 was determined by the dose-dependent stimulation of the proliferation of human MCF-7 cells is less than 0.5ng/ml, corresponding to a specific activity of >2.0×106 units/mg.

 

Reconstitution

It is recommended to reconstitute the lyophilized NRG1-B1 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

 

Stability

Lyophilized NRG1-B1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution NRG1-B1 should be stored at 4°C between 2-7 days and for future use below -18°C. Please avoid repeated freeze-thaw cycles.

 

Amino Acid Sequence

SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE

 

 

 

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Errors, changes and availability excepted.

 

 

Payment Methods

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Shipping

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