Human HGF (glycosylated, InCs) recombinant Protein

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Product Overview, Sizes and Prices

 

Protein

Synonyms: HGF, SF, HGFB, HPTA, F-TCF, DFNB39, Hepatocyte growth factor, Scatter factor, rh HGF.

Source: Insect cells

Purity: ≥ 95 % (SDS-PAGE, silver stained)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
2790.952.005 5 g 90 €
2790.952.010 10 g 150 €
2790.952.025 25 g 295 €
2790.952.100 100 g 440 €
2790.952.500 500 g 1.450 €
2790.952.199 1 mg 2.290 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

HGF, SF, HGFB, HPTA, F-TCF, DFNB39, Hepatocyte growth factor, Scatter factor, rh HGF.

 

Description of Human HGF (glycosylated, InCs)

Recombinant human Hepatocyte Growth Factor (HGF) is a 78.0 kDa disulfide-linked heterodimeric protein. HGF is a multifunctional polypeptide that acts in a paracrine fashion on a wide variety of cell types. Human HGF, also know as scatter factor, is a pleiotrophic cytokine that shows homology to the enzymes of the blood coagulation cascade. Hepatocytes have to be primed (e.g. TNF and IL-6) before they can fully respond to HGF. Recent studies suggest that HGF synergizes with FGF-basic in the induction of angiogenesis.

 

Biological Activity

The ED50 of ≤ 5 ng/ml was determined by scattering activity in MDCK cells. It corresponds to a specific activity of ≥ 2x105 units/mg.

 

Reconstitution

The lyophilized HGF is soluble in acetic acid 50mM. The lyophilized product should be reconstituted to a concentration of 100g/ml. It is recommended that further dilutions be made into buffer containing carrier protein (e.g. HSA ultra pure, 2835.958.xyz) or medium containing serum.

 

Stability

The lyophilized protein, though stable at room temperature, is best stored desiccated below -18C. Reconstituted HGF should be stored in working aliquots at -20C to -70C. Please avoid repeated freeze-thaw cycles.

 

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Amino Acid Sequence

alpha chain:
QRKRRNTIHE FKKSAKTTLI KIDPALKIKT KKVNTADQCA NRCTRNKGLP FTCKAFVFDK ARKQCLWFPF NSMSSGVKKE FGHEFDLYEN KDYIRNCIIG KGRSYKGTVS ITKSGIKCQP WSSMIPHEHS FLPSSYRGKD LQENYCRNPR GEEGGPWCFT SNPEVRYEVC DIPQCSEVEC MTCNGESYRG LMDHTESGKI CQRWDHQTPH RHKFLPERYP DKGFDDNYCR NPDGQPRPWC YTLDPHTRWE YCAIKTCADN TMNDTDVPLE TTECIQGQGE GYRGTVNTIW NGIPCQRWDS QYPHEHDMTP ENFKCKDLRE NYCRNPDGSE SPWCFTTDPN IRVGYCSQIP NCDMSHGQDC YRGNGKNYMG NLSQTRSGLT CSMWDKNMED LHRHIFWEPD ASKLNENYCR NPDDDAHGPW CYTGNPLIPW DYCPISRCEG DTTPTIVNLD HPVISCAKTK QLR

beta chain:
VVNGIP TRTNIGWMVS LRYRNKHICG GSLIKESWVL TARQCFPSRD LKDYEAWLGI HDVHGRGDEK CKQVLNVSQL VYGPEGSDLV LMKLARPAVL DDFVSTIDLP NYGCTIPEKT SCSVYGWGYT GLINYDGLLR VAHLYIMGNE KCSQHHRGKV TLNESEICAG AEKIGSGPCE GDYGGPLVCE QHKMRMVLGV IVPGRGCAIP NRPGIFVRVA YYAKWIHKII LTYKVPQS

 

Shipping symbol Shipped at room temperature

 

 

 

Biological Activity of Human HGF (glycosylated, InCs)

Fig 1: Measurement of scattering activity in MDCK cells by recombinant human HGF and a competitor. Values are the means (SD) of triplicate determinations and expressed as percentage of control.

Fig 1: Measurement of scattering activity in MDCK cells by recombinant human HGF and a competitor. Values are the means (SD) of triplicate determinations and expressed as percentage of control.

 

 

 

 

 

 

 

 

 

To buy Human HGF (glycosylated, InCs) please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button Shopping List & Order Form or the Shopping List Symbol in the top navigation to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable. Human HGF (glycosylated, InCs) is an alternative for the no longer available Promokine HGF, human, recombinant (Sf9) (C-64530).

 

All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.

 

Errors, changes and availability excepted.

 

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

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Content

 

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