Human IL-13 recombinant Protein

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Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: ALRH, BHR1, NC 30, Interleukin 13 (Trehalose)

Source: E. coli

Biological activity: ≥ 1 x 106units/mg

Purity: ≥ 95% (SDS-PAGE, RP-HPLC)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1550.951.002 2 µg 60 €
1550.951.010 10 µg 159 €
1550.951.199 1 mg 3.990 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

ALRH, BHR1, NC 30, Interleukin 13 (Trehalose)

 

Description of Human IL-13

Recombinant human IL-13 is a single, non-glycosylated polypeptide chain containing 112 amino acids with a molecular mass of 12 kDa. References show cross reactivity with Mouse, Monkey and Pig. IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. It shares many properties with IL-4.

 

Biological Activity

The ED50 of ≤ 1ng/ml was determined by the dose dependent proliferation of TF-1 cells. It corresponds to a specific activity of ≥ 1.0 x 106 units/mg.

 

Reconstitution

We recommend a quick spin followed by reconstitution in sterile Water at a concentration of 0.1 mg/ml, which can then be further diluted into other aqueous or buffered solutions.

 

Stability

The lyophilized protein is stable for at least 1 year from date of receipt if stored at -20°C to -80°C. Reconstituted IL-13 should be stored at 4°C if entire vial will be used within 1-2 weeks. It is stable for least 3 months when stored in working aliquots with a carrier protein at -20°C. Please avoid repeated freeze-thaw cycles.

 

Amino Acid Sequence

GPVPPSTALR ELIEELVNIT QNQKAPLCNG SMVWSINLTA GMYCAALESL INVSGCSAIE KTQRMLSGFC PHKVSAGQFS SLHVRDTKIE VAQFVKDLLL HLKKLFREGR FN

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

 

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Errors, changes and availability excepted.

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

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