Human IL-3, cct-premium (HSA) recombinant Protein

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Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: IL3, IL-3, MCGF, MULTI-CSF

Source: E. coli

Biological activity: ≥ 1 x 107 IU/mg

Purity: ≥ 98% (SDS-PAGE, silver stained)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1509.951.010 10 µg 190 € €
1509.951.050 50 µg 390 € €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

IL3, IL-3, MCGF, MULTI-CSF

 

Description of Human IL-3, cct-premium (HSA)

Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues. It is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.

 

Biological Activity

The ED50 of ≤ 0.1ng/ml was determined by the dose-dependent stimulation of the proliferation of TF-1 cells. It corresponds to a specific activity of ≥ 1 x 107 IU/mg.

 

Reconstitution

The lyophilized IL-3 should be reconstituted in water to a concentration not less than 100µg/ml. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.

 

Amino Acid Sequence

MAPMTQTTPL KTSWVNCSNM IDEIITHLKQ PPLPLLDFNN LNGEDQDILM ENNLRRPNLE AFNRAVKSLQ NASAIESILK NLLPCLPLAT AAPTRHPIHI KDGDWNEFRR KLTFYLKTLE NAQAQQTTLS LAIF

 

 

 

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Errors, changes and availability excepted.

 

 

Payment Methods

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Shipping

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Free shipping for orders above 500 € within Germany

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