Human Lactoferrin, Milk

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	Proteins Synonyms: LF, LFT, Lactotransferrin, Growth-inhibiting protein 12 Talalactoferrin Source: Human Milk Purity: ≥ 95% by SDS-PAGE Physical State: Lyophilized from 50 mM Tris-HCl, pH 8.0, with 0.2 M NaCl Manufacturer:  Athens Research & Technology	Article No. Size Price   16-13-120103-5MG 5 mg 105 € Please inquire for other vial sizes and custom vialing.

 

 

Produktdetails

Synonyms

LF, LFT, Lactotransferrin, Growth-inhibiting protein 12 Talalactoferrin

 

Description of Human Lactoferrin, Milk

Human Lactoferrin, Milk is a 82.4 kDa protein. Lactoferrin is a multifunctional glycoprotein abundantly present in milk, especially in colostrum, and plays a crucial role in the innate immune defense of breastfed infants. It exerts potent bacteriostatic and bactericidal effects in the intestinal tract by binding free iron, depriving pathogenic bacteria of this essential nutrient and thereby inhibiting their growth. Working synergistically with secretory IgA, lactoferrin helps protect the newborn’s gut from infections and supports the development of a healthy microbiome. In addition to its antimicrobial activity, lactoferrin acts as an iron-binding protein that facilitates the efficient absorption of dietary iron, contributing to the high bioavailability of iron in breast milk and reducing the risk of iron deficiency in infants. Beyond infancy, lactoferrin is being explored for therapeutic applications in treating infections, inflammatory bowel diseases, and iron metabolism disorders, as well as in functional foods and supplements to enhance immune function and support overall health.

 

Source

Prepared from human milk shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

 

Storage

For long term, store Human Lactoferrin, Milk at -20°C.

 

Applications

Iron Transport, Antimicrobial, Inflammation, Immunology.

 

Citations/Publications

Zhao, K. W., et al., (2019), 'HK2 Proximal Tubule Epithelial Cells Synthesize and Secrete Plasma Proteins Predominantly Through the Apical Surface', J Cell Biochem. 118(4): pp 924-933. Available at: doi: 10.1002/jcb.25786.
NCBI: https://www.ncbi.nlm.nih.gov/protein/P02788

 

Shipped with ice packs

 

Gel Scan of Human Lactoferrin, Milk

Fig. 1: SDS-PAGE Gel

 

 

Download Datasheet

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

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