Murine IL-12 p70 (glycosylated, HEK) recombinant Protein

Please log in to see the special conditions of your institution.

 

Mitarbeiterfoto

+49 (0) 40 . 43 20 84 48 0

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12.

Source: HEK

Purity: ≥ 95% (SDS-PAGE)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1545.962.002 2 µg 90 €
1545.962.010 10 µg 175 €
1545.962.199 100 µg 960 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12.

 

Description of Murine IL-12 p70 (glycosylated, HEK)

Interleukin-12 Murine Recombinant produced in HEK 293 cells is a glycosylated disulfide linked heterodimeric polypeptide containing 506 amino acids and having a molecular weight of 75 kDa comprised of disulfide-bonded 35 kDa (p35) and 40 kDa (p40) subunits.

 

Biological Activity

The ED 50 of 10-20 ng/ml was determined by the dose-dependent induced expression of CD25 on CD8+ mouse T cells, it corresponds to a specific activity of 5-10 x 104 units/mg.

 

Reconstitution

It is recommended to reconstitute the lyophilized murine IL12 in sterile distilled pyrogen free water at 100µg/ml, which can then be further diluted to other aqueous solutions.

 

Stability

Lyophilized mouse IL-12 although stable at room temperature for 3 weeks, should be stored below -18°C. Upon reconstitution IL12 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA, order number: 2835.955.xyz or 2835.958.xyz, or BSA, order number: 2835.919.xyz). Please avoid repeated freeze-thaw cycles.

 

Lupe Zoom

Amino Acid Sequence

p35Subunit :RVIPVSGPA RCLSQSRNLL KTTDDMVKTA REKLKHYSCT AEDIDHEDIT RDQTSTLKTC LPLELHKNES CLATRETSST TRGSCLPPQK TSLMMTLCLG SIYEDLKMYQ TEFQAINAAL QNHNHQQIIL DKGMLVAIDE LMQSLNHNGE TLRQKPPVGE ADPYRVKMKL CILLHAFSTR VVTINRVMGY LSSA.p40Su bunit:MWEL EKDVYVVEVD WTPDAPGETV NLTCDTPEED DITWTSDQRH GVIGSGKTLT ITVKEFLDAG QYTCHKGGET LSHSHLLLHK KENGIWSTEI LKNFKNKTFL KCEAPNYSGR FTCSWLVQRN MDLKFNIKSS SSSPDSRAVT CGMASLSAEK VTLDQRDYEK YSVSCQEDVT CPTAEETLPI ELALEARQQN KYENYSTSFF IRDIIKPDPP KNLQMKPLKN SQVEVSWEYP DSWSTPHSYF SLKFFVRIQR KKEKMKETEE GCNQKGAFLV EKTSTEVQCK GGNVCVQAQD RYYNSSCSKW ACVPCRVRS

 

Shipping symbol Shipped at room temperature

 

 

 

 

 

 

 

 

To buy Murine IL-12 p70 (glycosylated, HEK) please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button »Shopping List & Order Form« or the Shopping List Symbol in the top navigation to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.

 

All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.

 

Errors, changes and availability excepted.

 

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

This website uses cookies to store your Personal Shopping List. By using our website you accept the use of session cookies. Learn more
I accept all necessary cookies