Murine IL-12 p70 (glycosylated, HEK) recombinant Protein

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Product Overview, Sizes and Prices

 

Protein

Synonyms: NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12.

Source: HEK

Purity: ≥ 95% (SDS-PAGE)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1545.962.002 2 µg 65 €
1545.962.010 10 µg 159 €
1545.962.199 100 µg 960 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Edodekin-alpha, IL-12.

 

Description of Murine IL-12 p70 (glycosylated, HEK)

Interleukin-12 Murine Recombinant produced in HEK 293 cells is a glycosylated disulfide linked heterodimeric polypeptide containing 506 amino acids and having a molecular weight of 75 kDa comprised of disulfide-bonded 35 kDa (p35) and 40 kDa (p40) subunits.

 

Biological Activity

The ED 50 of 10-20 ng/ml was determined by the dose-dependent induced expression of CD25 on CD8+ mouse T cells, it corresponds to a specific activity of 5-10 x 104 units/mg.

 

Reconstitution

It is recommended to reconstitute the lyophilized murine IL12 in sterile distilled pyrogen free water at 100µg/ml, which can then be further diluted to other aqueous solutions.

 

Stability

Lyophilized mouse IL-12 although stable at room temperature for 3 weeks, should be stored below -18°C. Upon reconstitution IL12 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid repeated freeze-thaw cycles.

 

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Amino Acid Sequence

p35Subunit :RVIPVSGPA RCLSQSRNLL KTTDDMVKTA REKLKHYSCT AEDIDHEDIT RDQTSTLKTC LPLELHKNES CLATRETSST TRGSCLPPQK TSLMMTLCLG SIYEDLKMYQ TEFQAINAAL QNHNHQQIIL DKGMLVAIDE LMQSLNHNGE TLRQKPPVGE ADPYRVKMKL CILLHAFSTR VVTINRVMGY LSSA.p40Su bunit:MWEL EKDVYVVEVD WTPDAPGETV NLTCDTPEED DITWTSDQRH GVIGSGKTLT ITVKEFLDAG QYTCHKGGET LSHSHLLLHK KENGIWSTEI LKNFKNKTFL KCEAPNYSGR FTCSWLVQRN MDLKFNIKSS SSSPDSRAVT CGMASLSAEK VTLDQRDYEK YSVSCQEDVT CPTAEETLPI ELALEARQQN KYENYSTSFF IRDIIKPDPP KNLQMKPLKN SQVEVSWEYP DSWSTPHSYF SLKFFVRIQR KKEKMKETEE GCNQKGAFLV EKTSTEVQCK GGNVCVQAQD RYYNSSCSKW ACVPCRVRS

 

Shipping symbol Shipped at room temperature

 

 

 

 

 

 

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

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Errors, changes and availability excepted.

 

 

 

Payment Methods

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Shipping

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Free shipping for orders above 500 € within Germany

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