Rat FGF-basic, FGF-2 recombinant Protein

Please log in to see the special conditions of your institution.



+49 (0) 40 . 43 20 84 48 0


Product Overview, Sizes and Prices



Synonyms: FGF2, bFGF, FGF-2.

Source: E. coli

Purity: ≥ 98 % (SDS-PAGE, silver stained)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1370.970.010 10 g 60 €
1370.970.050 50 g 140 €
1370.970.200 200 g 280 €
1370.970.199 1 mg 990 €

Please inquire for other vial sizes and custom vialing.



Product Details


FGF2, bFGF, FGF-2.


Description of Rat FGF-basic, FGF-2

The FGF family is composed of at least 23 polypeptides that show a variety of biological activities towards cells of mesenchymal, neuronal and epithelial origin. All members are heparin-binding growth factors (HB-GF). Until the structure of basic fibroblast growth factor (bFGF/FGF-2) was determined, a number of synonyms were used to describe this growth factor. As is often the case, the nomenclature reflected the observed activities reported by individual groups. Basic FGF has been reported as leukemia growth factor, macrophage growth factor, endothelial growth factor and tumor angiogenesis factor. The eventual isolation and characterization of bFGF was done from soluble brain extracts. bFGF was found to have a molecular mass of 16.5 kDa and to be 154 amino acids in length. Interestingly, bFGF contains no hydrophobic leader sequence previously thought to be required for cell secretion. Basic FGF bears 55% homology to acidic FGF and also seems to exist in three forms: the 154 amino-acid form and two other truncated versions of 146 and 131 amino acids lacking the N-terminal 9 and 24 residues. Acidic and basic FGF compete for the binding to 125 kDa and 145 kDa receptor species. However, acidic FGF has a higher affinity for the 125 kDa species, while basic FGF has a higher affinity for the 145 kDa species. FGF receptor activation leads to the activation of MAP kinase and protein kinase C. FGFs induce the proliferative response in cells derived from mesoderm and neuroectoderm. Perhaps one of the most potentially significant applications of bFGF is related to its reported ability to induce angiogenesis. The cDNA of native rat FGF-2 (Ala11-Ser154) was cloned from total RNA derived from a rat embryo using standard protocols.


Biological Activity

The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells (HUVEC) by mouse FGF-2 has been determined to be in the range of 0.1-2 ng/ml.



The rat FGF-2 is supplied in lyophilized form and can be reconstituted with ddH2O at 50 g/mL. This solution can be diluted into other buffered solutions or stored frozen for future use.


Lupe Zoom

Amino Acid Sequence



Shipping symbol Shipped at room temperature









To buy Rat FGF-basic, FGF-2 (W1370970010, W1370970050, W1370970200, W1370970199) please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button Shopping List & Order Form or the Shopping List Symbol in the top navigation to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.


All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.


Errors, changes and availability excepted.




Payment Methods

Paying by bank transfer


We ship with UPS

Free shipping for orders above 500 € within Germany

This website uses cookies to store your Personal Shopping List. By using our website you accept the use of session cookies. Learn more
I accept all necessary cookies