EN
Rat Haptoglobin
Native whole molecule
Product Overview, Sizes and Prices | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteins Synonyms: Zonulin, HPT, HP, BP, HP2ALPHA2, HPA1S Source: Rat Serum Purity: ≥ 95% by SDS-PAGE Physical State: Salt-free lyophilized solid. Manufacturer: |
|
|||||||||||||||||||||
Athens Research & Technology
Produktdetails
Synonyms
Zonulin, HPT, HP, BP, HP2ALPHA2, HPA1S
Description of Rat Haptoglobin
Rat Haptoglobin is a 86 kDa protein. Rat haptoglobin is a plasma glycoprotein primarily responsible for binding free hemoglobin released during red blood cell breakdown, thereby preventing hemoglobin-induced oxidative tissue damage and facilitating its clearance via the reticuloendothelial system2. Structurally, rat haptoglobin is a heterotetramer composed of two alpha and two glycosylated beta subunits linked by disulfide bonds, and it exhibits significant polymorphism, resulting in multiple phenotypes with varying molecular weights and polymeric structures. These structural variants influence the protein’s antioxidant capacity and are linked to different susceptibilities to disease. Altered haptoglobin levels or function in rats are associated with hemolytic anemia, kidney injury due to hemoglobin accumulation, and increased risk of oxidative stress-related diseases. In biomedical research, rat haptoglobin serves as a biomarker for hemolytic conditions and inflammation, and is used in studies of oxidative stress, immune response, and as a model for understanding haptoglobin's role in human health and disease.
Source
Rat Serum used to purify Haptoglobin was obtained from healthy animals of US origin and under the care of a registered veterinarian.
Storage
For long term, store Rat Haptoglobin at ≤ -20°C.
Applications
ELISA, Protein Chemistry, Inflammation, Sickle Cell Anemia, Glycosylation, Stroke, Central Nervous System Injury, Diabetes, Cardiovascular Disease, In Vitro Diagnostic, Iron Metabolism, Cancer.
Citations/Publications
NCBI: https://www.ncbi.nlm.nih.gov/protein/P06866
Shipped with ice packs
Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.
To buy Rat Haptoglobin please click on the Shopping List Symbol right from the indicated price. This will add Rat Haptoglobin to your Shopping List. You can then click on the button »Shopping List & Order Form« to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.
For business customers only. All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.
Errors, changes and availability excepted.
Payment Methods
Paying by bank transfer
