SARS-CoV-2 Spike 1000-1200 (nCoV-S2 Spike 1000-1200, His-Tag) recombinant Protein

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Product Overview, Sizes and Prices

 

Protein

Synonyms: Novel Coronavirus 2019 Spike (AA 1000-1200), recombinant

Source: E. coli

Purity: ≥ 90% (SDS-PAGE)

Physical state: Sterile filtered, liquid

Manufacturer:  Active Bioscience

Article No. Size Price  
2012.V20.050 50 µg 170 €
2012.V20.250 250 µg 580 €
2012.V20.199 1 mg 1.490 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

Novel Coronavirus 2019 Spike (AA 1000-1200), recombinant

 

Description of SARS-CoV-2 Spike 1000-1200 (nCoV-S2 Spike 1000-1200, His-Tag)

Recombinant SARS-CoV-2 Spike Protein, AA 1000-1200 of the immunodominant region is derived from E.Coli and fused to a His-tag at the C-terminal end. SARS-CoV-2, formerly termed 2019-nCOV, causes the pandemic COVID-19 disease, a viral pneumonia.

The SARS-CoV-2 shares an 87% identity to two bat-derived severe acute respiratory syndrome 2018 (SARS-like) coronaviruses found in Zhoushan of eastern China. It is more distant from SARS-CoV (79%) identity and MERS-CoV (50%) identity. SARS-CoV-2 has an analogous receptor-binding domain-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans.

While bats are possibly the host of SARS-CoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the SARS-CoV-2 is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.

 

Stability

The protein is stable for at least 2 weeks at 0°C - 4°C, and therefore can be shipped on ice packs. Upon arrival it should be stored at -20 °C. Please avoid repeated freeze thaw cycles.

 

 

 

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Payment Methods

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Shipping

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