Human Urokinase Enzyme

Human Urokinase Enzyme, native

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+49 (0) 40 . 43 20 84 48 0

 

Product Overview, Sizes and Prices

 

Enzymes

Synonyms: Urokinase, Abbokinase, Urokinase-type Plasminogen Activator, uPA, EC 3.4.21.73, UK.

Source: Human Urine

Biological Activity: ≥ 150 000 IU/mg

Purity: ≥ 90 %

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No.SizePrice 
4097.959.100 100 µg 175 €
4097.959.199 1 mg 350 €
4097.959.599 5 mg 990 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

Urokinase, Abbokinase, Urokinase-type Plasminogen Activator, uPA, EC 3.4.21.73, UK.

 

Description of Human Urokinase

Human Urokinase (native) derived from human urine is a 54 kDa two-chain glycoprotein containing 411 amino acids with 12 disulfide bonds. Urokinase (UK) is a serine protease, which is one of the biological plasminogen activators. It is involved in several biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. Urokinase is inhibited by the plasminogen activator inhibitors PAI-1 (1797.950.xyz) and PAI-2 (1798.950.xyz). It has been found that the expression of Urokinase and PAI-1 is increased in some cancer patients.

 

Human Virus Test

Urine has been tested and found negative for antibodies to HIV-1, HIV-2, HCV, and non-reactive for HBsAg.

 

Biological Activity

The biological activity is ≥ 150 000 IU/mg. One unit is defined as the amount of enzyme equal to an international standard tested by the fibrinolytic method of Johnson, et al. PMID: 5791803.

 

Reconstitution

We recommend a quick spin followed by reconstitution in sterile water to a concentration of at least 100µg/ml, which can then be further diluted to other aqueous solutions. Do not vortex.

 

Stability

Lyophilized Urokinase is stable at room temperature for up to 3 weeks, and at least until the lot specific expiry date if stored below -18°C. Upon reconstitution Urokinase can be stored at 4°C for 2-7 days and below -18°C for future use. Please avoid repeated freeze-thaw cycles.

 

Shipping symbol Shipped at room temperature

 

 

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

To buy Human Urokinase Enzyme please click on the Shopping List Symbol right from the indicated price. This will add Human Urokinase Enzyme to your Shopping List. You can then click on the button »Shopping List & Order Form« to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable.

 

 

For business customers only. All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.

 

Errors, changes and availability excepted.

 

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

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