Rabbit Anti-Cathepsin D Polyclonal Antibody

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	Polyclonal Antibody (PAB) Source: Rabbit Physical State: Liquid phosphate buffered saline with 0.05% NaN3 as a preservative Manufacturer:  Athens Research & Technology	Article No. Size Price   01-12-030104-1ML 1 ml 315 €

 

 

Produktdetails

Description of Rabbit Anti-Cathepsin D

Rabbit Anti-Cathepsin D is a 150 kDa protein. Form: Ig Fraction (Standard Antisera) obtained by ammonium sulfate precipitation.

 

Source

All animals used in the production of this material are Specific Pathogen Free (SPF) and of U.S. origin. They are sourced from a USDA-registered research facility operating in full compliance with USDA regulations.

 

Storage

For long term, store Rabbit Anti-Cathepsin D at +2 to 8°C.

 

Applications

ELISA, Western Blot, In Vitro Diagnostic.
ELISA working dilution: > 1:16000 by indirect ELISA.
Western Blot working dilution: At a dilution of 1:4000 the antibody reacts with 0.075, 0.15, and 0.3 µg human liver cathepsin D and does not react with cathepsins B, H or L.

 

Immunogen

The Cathepsin D immunogen used to prepare this antibody was purified in the Athens Research & Technology laboratory. It is a native protein, whole molecule, isolated from human liver.

 

Citations/Publications

Eriksson, I., et al., (2020), 'Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins', Cell Death and Disease 11: pp 370. Available at: https://doi.org/10.1038/s41419-020-2527-8
Wäster, P., et al., (2017), 'UV radiation promotes melanoma dissemination mediated by the sequential reaction axis of cathepsins–TGF-β1–FAP-α', British Journal of Cancer 117: pp 535–544. Available at: doi: 10.1038/bjc.2017.182 
Wäster, P., et al., (2016), 'Extracellular vesicles are transferred from melanocytes to keratinocytes after UVA irradiation', Scientific Reports. 6:27890. Available at: DOI: 10.1038/srep27890
NCBI: https://www.ncbi.nlm.nih.gov/protein/P07339

 

Shipped with ice packs

 

 

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Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

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