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Human CXCL16 recombinant Protein
Human CXCL 16, recombinant
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Proteins Synonyms: SR-PSOX Chemokine (C-X-C Motif) Ligand 16, Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein, Transmembrane Chemokine CXCL16, Small-Inducible Cytokine B16, CXC Chemokine Ligand 16, C-X-C Motif Chemokine 16, CXCLG16. Source: E. coli Biological Activity: ≥ 8.3x104 units/mg Purity: ≥ 97 % (SDS-PAGE) Physical state: Lyophilized Manufacturer: |
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Active Bioscience
Product Details
Synonyms
SR-PSOX Chemokine (C-X-C Motif) Ligand 16, Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein, Transmembrane Chemokine CXCL16, Small-Inducible Cytokine B16, CXC Chemokine Ligand 16, C-X-C Motif Chemokine 16, CXCLG16.
Description of Human CXCL16
Recombinant human CXCL16 is a 10.1 kDa protein containing 89 amino acids. It is a member of the CXC chemo-kine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets dur-ing inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six cysteine residues including the four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmic domain and transmembrane sequence containing approximately 20 amino acids. The extracellular portion of CXCL16 contains a chemokines domain and an extended C-terminal “mucin-like stalk” sequence. The extracellular domain contains 89 amino acid residues (86 a.a. for the murine homolog).
Biological Activity
The ED50 of ≤ 12ng/ml was measured by its ability to chemoattract mouse CXCR6-transfected mouse BaF3 cells.
Reconstitution
We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Stability
Lyophilized human CXCL16, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL16 can be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage we recommend to add a carrier protein (0.1% HSA, order number: 2835.955.xyz or 2835.958.xyz, or BSA, order number: 2835.919.xyz). Please avoid repeated freeze-thaw cycles.
Amino Acid Sequence
NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP
Shipped at room temperature
Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.
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Payment Methods
Paying by bank transfer
