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Human IFN-lambda-2 / IL-28A recombinant Protein
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Protein Synonyms: Interleukin-28A, IL-28A, IFN-Lambda 2, IFN-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20. Source: E. coli Biological activity: See below Purity: ≥ 85% (SDS-PAGE, RP-HPLC) Physical state: Lyophilized Manufacturer: |
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Active Bioscience
Product Details
Synonyms
Interleukin-28A, IL-28A, IFN-Lambda 2, IFN-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20.
Description of Human IFN-lambda-2 / IL-28A
Recombinant human Interferon-lambda2 (IFN-?2) is a 19.6 kDa protein containing 174 amino acid residues. IFN-lambda-1, -2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. (Kotenko, SV. Et al. Nat Immunology 2003 [1] p. 69-77).
Biological Activity
Determined by its ability to activate STAT following receptor-ligand interaction.
Reconstitution
We recommend a quick spin follow reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for one week or -20° for future use.
Stability
The lyophilized protein is stable at room temperature for a few weeks, but best stored at -20°C. Reconstituted human IFN-?2 should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA, order number: 2835.955.xyz or 2835.958.xyz, or BSA, order number: 2835.919.xyz). Please avoid repeated freeze-thaw cycles.
Amino Acid Sequence
VPVARLHGAL PDARGCHIAQ FKSLSPQELQ AFKRAKDALE ESLLLKDCRC HSRLFPRTWD LRQLQVRERP MALEAELALT LKVLEATADT DPALVDVLDQ PLHTLHHILS QFRACIQPQP TAGPRTRGRL HHWLYRLQEA PKKESPGCLE ASVTFNLFRL LTRDLNCVAS GDLCV
Shipped at room temperature
To buy Human IFN-lambda-2 / IL-28A please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button »Shopping List & Order Form« or the Shopping List Symbol in the top navigation to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable. Human IFN-lambda-2 / IL-28A is an alternative for the no longer available Promokine IFN-lambda-2 (IL-28A), human, recombinant (E. coli) (C-60732).
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Errors, changes and availability excepted.
Payment Methods
Paying by bank transfer
