Human IL-4 recombinant Protein

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Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: IL4, BSF1, IL-4, BCGF1, BSF-1, BCGF-1

Source: E. coli

Purity: ≥ 98 % (SDS-PAGE, silver stained)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1518.950.005 5 µg 60 € €
1518.950.025 25 µg 150 € €
1518.950.050 50 µg 290 € €
1518.950.100 100 µg 470 € €
1518.950.200 200 µg 690 € €
1518.950.500 500 µg 1.490 € €
1518.950.199 1 mg 2.100 € €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

IL4, BSF1, IL-4, BCGF1, BSF-1, BCGF-1

 

Description of Human IL-4

IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 130 amino acid residues

 

Biological Activity

The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is 0.1-0.5ng/ml.

 

Reconstitution

The lyophilized IL-4 should be reconstituted in water to a concentration not less than 100µg/ml. This solution can be diluted into other buffered solutions or stored at -20 °C for future use.

 

Amino Acid Sequence

MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS

 

 

 

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Errors, changes and availability excepted.

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

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