Human/Murine/Rat Activin A recombinant Protein

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+49 (0) 40 . 43 20 84 48 0

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: Inhba, Inhibin beta A, FSH releasing protein, Erythroid Differentiation Factor (EDF).

Source: E. coli

Biological activity: ≥ 6 x 105 IU/mg

Purity: ≥ 95 % (SDS-PAGE)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1100.950.002 2 g 60 €
1100.950.010 10 g 159 €
1100.950.050 50 g 405 €
1100.950.100 100 g 670 €
1100.950.199 1 mg 3.250 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

Inhba, Inhibin beta A, FSH releasing protein, Erythroid Differentiation Factor (EDF).

 

Description of Human/Murine/Rat Activin A

The active form of recombinant human Activin A is a 26.2 kDa disulfide-linked homodimer of two beta A chains, each containing 117 amino acid residues, belonging to the TGF-beta family. It exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, follistatin.

 

Biological Activity

The ED50 of ≤ 1,5 ng/ml was determined by its ability to induce cytotoxicity of MPC-11 cell. It corresponds to a specific activity of ≥ 6 x 105 U/mg.

 

Reconstitution

We recommend a quick spin followed by reconstitution in water to a concentration of 100g/ml. This can be stored 4C for 1 week or -20C for future use. For long term storage we recommend to add a carrier protein (0.1% HSA, order number: 2835.955.xyz or 2835.958.xyz, or BSA, order number: 2835.919.xyz).

 

Stability

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20C. Reconstituted Activin A should be stored in working aliquots at -20C. Please avoid repeated freeze-thaw cycles.

 

Lupe Zoom

Amino Acid Sequence

MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS

 

Shipping symbol Shipped at room temperature

 

 

 

 

 

 

 

 

To buy Human/Murine/Rat Activin A please click on the Shopping List Symbol right from the indicated price. This will add the product to your Shopping List. You can then click on the button Shopping List & Order Form or the Shopping List Symbol in the top navigation to ask for a quote. We will send you your quote as soon as possible. Our offer will include institutional discounts where applicable. Human/Murine/Rat Activin A is an alternative for the no longer available Promokine Activin A, human, recombinant (E. coli) (C-60066).

 

All prices are net prices (excluding VAT). Final prices in our quote will contain VAT plus shipping costs if applicable. For further information please go to our Shipping page.

 

Errors, changes and availability excepted.

 

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

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