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TPO Alternative Peptide
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Peptide-Alternative for Recombinant Human TPO Synonyms: TPO agonist Source: Chemical Synthesis Purity: ≥ 95% (HPLC) Physical State: Lyophilized Manufacturer: |
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PeptiGrowth
Produktdetails
Synonyms
TPO agonist
Description of TPO Alternative Peptide
1-2.6 times stronger activity than the rTPO at mass conc. (ng/mL). Hematopoietic stem cells (HSCs), Platelets (megakaryocytes), iPSC-derived T/NK cells, or macrophages (not autologous ones).
Physcial State
Lyophilized from 0.2 µm filtered DMSO solution.
Biological Activity
Measured by its ability to induce phosphorylation of ERK in the downstream signaling of the TPO signaling pathway, as well as by the reporter gene activation assay on the JAK2-STAT5 signaling pathway. The expected ED50 for these effects is 0.25~1.5 ng/mL. Determine optimal concentrations for individual applications.
Reconstitution
Reconstitute at 100~200 µg/mL in DMSO. Centrifuge the vial before opening. Rinse the inside of the vial thoroughly with DMSO. Example: a 100 µg/mL solution can be prepared by reconstituting 10 µg of peptide in 100 µL DMSO.
Shipped with ice packs
| Fig. 1: ERK phosphorylation |
| Fig. 2: Reporter gene activation |
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Errors, changes and availability excepted.
Payment Methods
Paying by bank transfer
