Human Relaxin-2 recombinant Protein

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Phone: +49 (0) 40 . 43 20 84 48 0

E-Mail: info@active-bioscience.de

 

Product Overview, Sizes and Prices

 

Protein

Synonyms: Prorelaxin H2, RLN2, H2, RLXH2, H2-RLX

Source: E. coli

Biological activity: No suitable assay available

Purity: ≥ 98 % (SDS-PAGE, HPLC)

Physical state: Lyophilized

Manufacturer:  Active Bioscience

Article No. Size Price  
1996.950.005 5 µg 60 €
1996.950.025 25 µg 159 €
1996.950.199 1 mg 2.550 €

Please inquire for other vial sizes and custom vialing.

 

 

Product Details

Synonyms

Prorelaxin H2, RLN2, H2, RLXH2, H2-RLX

 

Description of Human Relaxin-2

Recombinant human Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain. Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth.

 

Biological Activity

Data not available. Please also check 1997.950.xyz or 1997.952.xyz for use in cell culture.

 

Reconstitution

We recommend a quick spin followed by reconstitution in sterile filtered water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% HSA) and store in working aliquots at -20°C to -80°C.

 

Stability

The lyophilized protein is stable at room temperature for up 1 month and at 4°C up to 6 months. Working aliquots stored with a carrier protein are stable for at least 12 months at -20°C to -80°C. Please avoid repeated freeze-thaw cycles.

 

Amino Acid Sequence

A-Chain: QLYSALANKC CHVGCTKRSL ARFC
B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
Interchain disulfid bonds: 35 <-> 172 und 47 <-> 185

 

 

 

 

 

Usage: For research use only. Not for use in diagnostic or therapeutic procedures. Not for human use.

 

 

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Errors, changes and availability excepted.

 

 

Payment Methods

Paying by bank transfer

Shipping

We ship with UPS

Free shipping for orders above 500 € within Germany

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